Modern management does not provide the same level of control that IT is used to with AD domain-joined PCs. Depending on how you approach PC management, this might be an issue for you or it might not.

The number of MDM policies is increasing with each Windows 10 release and you can now deploy a subset of Group Policies via MDM. There are 3rd party solutions that can deploy traditional Group Policy to non-domain joined PCs, for example, PolicyPak.